Taking estrogen can be important for some people, but does it cause weight gain? October 4, 2023, 5:30 pm One of the side effects some people worry about when taking estrogen is whether it contributes to weight gain. Experts say you shouldn’t be concerned. See more Previous article Sweating cools us down, but does it burn calories? Next article Does the ‘healthiest diet’ exist? Why it’s so important to consider things other than food.